Dottorato in Medicina Molecolare

[Castella B, Foglietta M, Sciancalepore P, Rigoni M, Coscia M, Griggio V, Vitale C, Ferracini R, Saraci E, Omedè P, Riganti C, Palumbo A, Boccadoro M, Massaia M.  Anergic bone marrow Vgamma9Vdelta2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma. Oncoimmunology. 2015 May 26;4(11):e1047580. eCollection 2015 Nov.]

[Rigoni M, Riganti C, Vitale C, Griggio V, Campia I, Robino M, Foglietta M, Castella B, Sciancalepore P, Buondonno I, Drandi D, Ladetto M, Boccadoro M, Massaia M, Coscia M. Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells. Oncotarget. 2015 Oct 6;6(30):29833-46. doi: 10.18632/oncotarget.4006]

[Coscia M, Vitale C, Peola S, Foglietta M, Rigoni M, Griggio V, Castella B, Angelini D, Chiaretti S, Riganti C, Guarini A, Drandi D, Ladetto M, Bosia A, Foà R, Battistini L, Boccadoro M, Fournié JJ, Massaia M. Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells. Blood. 2012; 120(16):3271-9]

[Marta Coscia, Francesca Pantaleoni, Chiara Riganti, Candida Vitale, Micol Rigoni, Silvia Peola, Barbara Castella, Myriam Foglietta, Valentina Griggio, Daniela Drandi, Marco Ladetto, Amalia Bosia, Mario Boccadoro, and Massimo Massaia. IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells. Leukemia. 2011 May;25(5):828-37.]

[Vitale C, Griggio V, Riganti C, Campia I, Robino M, Rigoni M, Sciancalepore P, Foglietta M, Castella B, Boccadoro M, Massaia M, Coscia M. The Mevalonate Metabolic Pathway and the CXCL12/CXCR4 Axis Reciprocally Interact and Are Implicated in Fludarabine Resistance of Chronic Lymphocytic Leukemia Cells. Blood (ASH Annual Meeting Abstract) 2014 124 (21)]

[Griggio V, Mandili G, Vitale C, Capello M, Robino M, Rigoni M, Foglietta M, Castella B, Sciancalepore P, Macor P, Novelli F, Boccadoro M, Massaia M, Coscia M. Identificazione e caratterizzazione funzionale delle risposte immuni anticorpali indotte da auto antigeni nella leucemia linfatica cronica. Haematologica 2014. 99(s2):s47 XIII Congress of the Italian Society of Experimental Hematology – Rimini, Italy, October 15-17 2014 Oral Comunication]

[Castella B, Foglietta M, Sciancalepore P, Rigoni M, Coscia M, Vitale C, Griggio V, Canepari ME, Robino M, Massaia M. Role of PD-1/PD-L1 axis in the immune paresis of bone marrow Vγ9Vδ2 T cells in multiple myeloma. Haematologica 2014. 99(s2):s24 XIII Congress of the Italian Society of Experimental Hematology – Rimini, Italy, October 15-17 2014]

[Rigoni M, Riganti C, Griggio V, Coscia M, Castella B, Foglietta M, Vitale C, Sciancalepore P, Robino M, Boccadoro M, Massaia M. The association of dexamethasone + simvastatin to overcome environment-mediated chemoresistance of chronic lymphocytic leukemia (CLL) cells. Haematologica 2014. 99(s2):s70 XIII Congress of the Italian Society of Experimental Hematology – Rimini, Italy, October 15-17 2014]

[Griggio V, Mandili G, Vitale C, Capello M, Robino M, Rigoni M, Foglietta M, Castella B, Sciancalepore P, Canepari ME, Novelli F, Boccadoro M, Massaia M, Coscia M. Identification and functional characterization of tumor specific antibody responses in chronic lymphocytic leukemia. Haematologica 2014. 99(s1):54. 19th Congress of the European Hematology Association 11-15 June 2014, Milano (Italy)]

[Griggio V, Mandili G, Vitale C, Capello M, Novelli F, Boccadoro M, Massaia M, Coscia M. Serological proteome analysis (SERPA) as a tool for the identification of tumor antigens capable of eliciting immune responses in chronic lymphocytic leukemia (CLL). Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00935]

[Coscia M, Griggio V, Capello M, Vitale C, Linty F, Cappello P, Mandili G, Castella B, Foglietta M, Rigoni M, Sciancalepore P, Robino M, Ruggeri M, Drandi D, Omedè P, Ladetto M, Novelli F, Boccadoro M, Massaia M. Identification of Novel Tumor-Associated Antigens in Chronic Lymphocytic Leukemia (CLL) by Serological Proteome Analysis (SERPA).Blood (ASH Annual Meeting Abstracts) 2012 120.]

[Coscia M, Rigoni M, Riganti C, Vitale C, Campia I, Griggio V, Foglietta M, Castella B, Sciancalepore P, Canepari ME, Robino M, Drandi D, Ladetto M, Bosia A, Boccadoro M, Massaia M. The Mevalonate Pathway and Downstream Signal Transducers As Therapeutic Targets to Overcome Multidrug Resistance in Chronic Lymphocytic Leukemia (CLL). Blood (ASH Annual Meeting Abstracts) 2012 120.]

[Griggio V; Capello M; Vitale C; Linty F; Cappello P; Mandili G ; Castella B; Foglietta M; Rigoni M; Sciancalepore P; Drandi D; Ruggeri M; Omedè P; Ladetto M; Novelli F; Boccadoro M; Massaia M; Coscia M. Serological Proteome Analysis (SERPA) as a tool for the identification of novel tumor antigens in chronic lymphocytic leukemia (CLL). Haematologica 2012. 97(s2):26. XII Congress of the Italian Society of Experimental Hematology – Rome, Italy, October 17-19 2012 Oral Comunication]

[Rigoni M; Coscia M, Riganti C; Campia I; Vitale C; Peola S; Castella B; Griggio V; Panatleoni F; Sciancalepore P; Drandi D; Ladetto M; Bosia A; Boccadoro M; Massaia M. The mevalonate pathway as a metabolic target to circumvent multidrug-resistance in chronic lymphocytic leukemia cells (CLL). Haematologica 2012. 97(s2):28.XII Congress of the Italian Society of Experimental Hematology – Rome, Italy, October 17-19 2012.]

[Castella B, Foglietta M, Sciancalepore P, Coscia M, Vitale C, Rigoni M, Griggio V, Canepari M.E, Massaia M. Immunoparesis of bone marrow Vγ9Vδ2 T cells in human myeloma. Book of abstracts. Fifth International Gamma-Delta T-Cell Conference, May 31 – 2 June 2012, Freiburg, Germany.]

[Vitale C, Coscia M, Peola S, Foglietta M, Rigoni M, Griggio V, Castella B, Angelini D, Chiaretti S, Riganti C, Guarini A, Drandi D, Ladetto M, Bosia A, Foà R, Battistini L, Boccadoro M, Fournié JJ, Massaia M. Disfunctional Vγ9Vδ2 T cells are associated with increate mevalonate pathway activity in tumor cells and negative predictors of time to first treatment in chronic lymphocytic leukemia (CLL). Book of abstracts. Fifth International Gamma-Delta T-Cell Conference, May 31 – 2 June 2102, Freiburg, Germany.]

[Sciancalepore P, Castella B, Foglietta M, Vitale C, Rigoni M, Griggio V, Canepari ME, Coscia M, Massaia M. Vγ9Vδ2 T-cell proliferation driven by soluble isopentenyl pyrophosphate (IPP) released by dendritic cells (DC) treated with zoledronic acid. Book of abstracts. Fifth International Gamma-Delta T-Cell Conference, May 31 – 2 June 2012, Freiburg, Germany.]

[Coscia M, Rigoni M, Riganti C, Campia I, Vitale C, Griggio V, Peola S, Castella B, Sciancalepore P, Drandi D, Ladetto M, Bosia A, Boccadoro M, Massaia M (2011). The mevalonate pathway as a metabolic target to circumvent multidrug-resistance in chronic lymphocytic leukemia cells. BLOOD, In: Abstract book. San Diego, CA, USA, 10-12 December 2011, vol. 118, p. 735]

[Coscia M, Griggio V, Capello M, Vitale C, Linty F, Peola S, Cappello P, Castella B, Rigoni M, Sciancalepore P, Drandi D, Ruggeri M, Omedè P, Ladetto M, Novelli F, Boccadoro M, Massaia M (2011). Identification by serological proteome analysis (SERPA) of novel tumor associated antigens in chronic lymphocytic leukemia. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, In: Abstract book. Houston, TX, USA, 28-30 October 2011, vol. 11(s2), p. s176-s177]

[Coscia M, Rigoni M, Riganti C, Campia I, Vitale C, Griggio V, Peola S, Castella B, Pantaleoni F, Sciancalepore P, Drandi D, Omedè P, Ladetto M, Bosia A, Boccadoro M, Massaia M. (2011). Accelerated activity of the mevalonate pathway supports the immune escape and multidrug-resistance phenotype of IGHV unmutated chronic lymphocytic leukemia cells. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, In: Abstract Book. Houston, TX, USA, 28-30 October 2011, vol. 11(s2), p. s182]

[Griggio V, Capello M, Linty F, Vitale C, Peola S, Cappello P, Castella B, Rigoni M, Sciancalepore P, Drandi D, Ruggeri M, Omedè P, Ladetto M, Novelli F, Boccadoro M, Massaia M, Coscia M (2011). Identification by serological proteome analysis (SERPA) of tumor-associated antigens eliciting antibody-responses in chronic lymphocytic leukemia. HAEMATOLOGICA, In: Abstract book. Napoli, Italia, 16-19 Ottobre 2011, vol. 96(s3), p. 77]

[Rigoni M, Coscia M, Riganti C, Campia I, Vitale C, Peola S, Castella B, Griggio V, Pantaleoni F, Sciancalepore P, Drandi D, Ladetto M, Bosia A, Boccadoro M, Massaia M. (2011). Targeting the mevalonate pathway and downstream signaling pathways as a strategy to circumvent multidrug-resistance in CLL cells. HAEMATOLOGICA, In: Abstract book. Napoli, Italia, 16-19 Ottobre 2011, vol. 96(s3), p. 143]

[Coscia M, Griggio V, Capello M, Linty F, Vitale C, Peola P, Castella B, Rigoni M, Drandi D, Ruggeri M, Omedé P, Ladetto M, Novelli F, Boccadoro M, Massaia M. (2011). Serological proteome analysis (SERPA) for the identification of novel tumor-associated antigens in chronic lymphocytic leukemia. ANNALS OF ONCOLOGY, In: Abstract book. Lugano, Switzerland, 15-18 June 2011, vol. 22(s4), p. iv143-iv147]

[Coscia M, Griggio V, Capello M, Linty F, Vitale C, Peola S, Cappello P, Castella B, Rigoni M, Sciancalepore P, Drandi D, Ruggeri M, Omedè P, Ladetto M, Novelli F, Boccadoro M, Massaia M (2011). Serological proteome analysis (SERPA) for the identification of tumor-associated antigens eliciting antibody-responses in chronic lymphocytic leukemia. HAEMATOLOGICA, In: Abstract Book. London, UK, 6-9 June 2011, vol. 96(s2), p. 273-274]

[Coscia M, Rigoni M, Riganti C, Campia I, Vitale C, Peola P, Castella B, Griggio V, Pantaleoni F, Sciancalepore P, Drandi D, Ladetto M, Bosia A, Boccadoro M, Massaia M (2011). Impact of the mevalonate pathway and Hif/Pgp axis in microenvironment-mediated modulation of multidrug-resistance in CLL cells. HAEMATOLOGICA, In: Abstract Book. London, UK, 6-9 June 2011, vol. 96(s2), p. 33-34]

[Coscia M, Pantaleoni F, Riganti C, Vitale C, Rigoni M, Peola S, Drandi D, Ladetto M, Ruggeri M, Griggio V, Castella B, Sciancalepore P, Omedè P, Bosia A, Boccadoro M, Massaia M. (2011). IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and depend from the anti-apoptotic effect of environmental signals. HAEMATOLOGICA, In: Abstract Book. London, UK, 6-9 June 2011, vol. 96(s2), p. 484-485]

[Coscia M, Capello M, Griggio V, Linty F, Vitale C, Peola S, Castella B, Rigoni M, Drandi D, Ruggeri M, Omedé P, Ladetto M, Novelli F, Boccadoro M, Massaia M. (2010). Identification by serological proteome analysis (SERPA) of tumor-associated antigens eliciting antibody responses in chronic lymphocytic leukemia (CLL). BLOOD, In: Oral session. Orlando, FL, DEC 04-07, 2010, vol. 116, p. 917]

 

[19th Congress of the European Hematology Association 11-15 June 2014, Milano (Italy)]

[XII  Congress of the Italian Society of Experimental Hematology – Rimini, Italy, October 15-17 2014 (Oral Comunication)]

 

[International Congress of Immunology (ICI), Milano, 22-27 Agosto 2013 (Poster)]

[XII Congress of the Italian Society of Experimental Hematology – Rome, Italy, October 17-19 2012 (Oral Comunication)Under 40 in Hematology, Napoli, 15-16 Ottobre 2012 (Poster)]

[5th International Gamma-Delta T-Cell Conference” - Freiburg, Germany, 31 May to 02 June 2012]

[43° Congresso Nazionale SIE (Società Italiana di Ematologia) – Napoli, Mostra D’Oltremare, 16-17 Ottobre 2011]

[“5^th Cervo Preclinical Working Conference - Aminobisphosphonates in infections and cancer: from E. Coli to Multiple Myeloma” (Cervo, Imperia, 6-8 Ottobre 2011)]

[I° Convegno Regionale – Nuove frontiere in Medicina: la Medicina di Genere in Cardiologia, Farmacologia, Oncologia, Endocrinologia, Pneumologia, Immunologia (Torino, 26 Gennaio 2011, Centro Congressi e Convegni “MOLINETTE INCONTRA”)]

[“4^th Cervo Preclinical Working Conference - Antitumor Activity of Aminobisphosphonates: from Benches, to the Bedside, and Back ” (Cervo, Imperia, 1-3 Ottobre 2009)]

[Unmet clinical needs: Basic Scientists meet Clinicians to fill the gap. Molecular Biotechnology Center (MBC), 29 October 2014.]

[Whole-genome approaches for basic and applied research. Seminari del Dipartimento di Biotecnologie Molecolari e Scienze per la Salute. Molecular Biotechnology Center (MBC), 22 October 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Cloni mielomatosi e maree clonali (Dr.ssa Marina Ruggeri) 9 Gennaio 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Una nuova funzione per un vecchio gene: ruolo di ABCA1 nell’attivazione dei linfociti T Vγ9Vδ2 (Dr.ssa Patrizia Sciancalepore) 6 Febbraio 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Rethinking PCR: Minimal Residual Disease (MRD) detection by ddPCR, the latest offspring of PCR (Dr.ssa Daniela Drandi) 6 Marzo 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Analisi dei processi informativi tra il COES ed il laboratorio di Ematologia (Dr Gian Maria Zaccaria) 8 Maggio 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Ricostituzione immunologica nel paziente allotrapiantato (Dr Benedetto Bruno) 24 Luglio 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Criopreservazione (Dr Valter Redoglia) 25 Settembre 2014.]

[Ematolab (Incontri di aggiornamento e confronto sulla ricerca di laboratorio), Divisione Universitaria di Ematologia (Prof. Boccadoro). Next Generation Sequencing and MRD Monitoring (Dr.ssa Elisa Genuardi) 3 Novembre 2014.]

[Relatore: Rossana Maffei - Crosstalk between endothelial cells and chronic lymphocytic leukemia B cells: clinical and pathogenetic implications - Ospite: HuGef (13 Novembre 2013)

[Relatore: Ethan M. Shevach - Regulatory/Suppressor T cells: what do they really do - Ospite: Prof. Guido Forni (27 Marzo 2012)]

[Relatore: Giuseppe Maruccio - Multipurpose biochip toward on-chip medicine - Ospite: Prof. Francesco Novelli (31 Gennaio 2012)]

[Relatore: Pier Giuseppe Pelicci - Regulation of self renewal in cancer stem cells - Ospite: Prof. Corrado Tarella (25 Gennaio 2012)]

[“Un pomeriggio con la citometria a flusso. Applicazioni per la ricerca.”  (Torino, A.O. San Giovanni Battista, 5 Maggio 2010)]

[“La sicurezza nel laboratorio di analisi” - Workshop Teorico Pratico (organizzato da PBI international). (Milano, Dicembre 2008)]