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Lucia D'Amico

  • Dottorato: 24° ciclo
  • Matricola: 265693

Tesi di dottorato

CHARACTERIZATION OF BREAST CANCER STEM CELLS ABILITY TO METASTATIZE TO BONE: "A HUMAN IN MICE MODEL" OF BONE METASTATIS

Tutor: Riccardo Ferracini

Relatore: Mirella Giovarelli

Data discussione tesi: 28/01/2013

Attività di ricerca

1. D'Amelio P, Tamone C, Sassi F, D'Amico L, Roato I, Patanè S, Ravazzoli M, Veneziano L, Ferracini R, Pescarmona GP, Isaia GC. “Teriparatide increases the maturation of circulating osteoblast precursors”. Osteoporos Int. 2012 Apr;23(4):1245-53

2. D'Amelio P, Cristofaro MA, D'Amico L, Veneziano L, Roato I, Sassi F, Bisignano G, Saracco M, Pellerito R, Patane S, Ferracini R, Pescarmona GP, Isaia GC. “Iloprost modulates the immune response in systemic sclerosis”. BMC Immunol. 2010 Dec 15;11(1):62.
 
3. Roato I., Porta F., Mussa A. , D'Amico L., Fiore L., Garelli D., Spada M., Ferracini R. “Bone impairment in phenylketonuria is characterized by circulating osteoclast precursors and activated T cell increase”. Plos One  2010 Nov 30;5(11):e14167

4. D’Amelio P, Roato I, D’Amico L. Veneziano L, Suman E, Sassi F, Bisignano G, Ferracini R, Gargiulo G, Castoldi F, Pescarmona GP, Isaia GC. “Bone and bone-marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures”. Osteoporosis Int., 2010 Nov 30, 10-1496-7.

5. I. Roato , D. Caldo , L. D’Amico , P. D’Amelio , L. Godio , S. Patanè , F. Astore , G Grappiolo , M.Boggio , R. Scagnelli , L. Molfetta , R. Ferracini. “Osteoclastogenesis in peripheral blood mononuclear cell cultures of periprosthetic osteolysis patients and the phenotype of T cells localized in periprosthetic tissues.” Biomaterials 2010 Oct;31(29):7519-25.

6. Roato I, Caldo D, Godio L, D'Amico L, Giannoni P, Morello E, Quarto R, Molfetta L, Buracco P, Mussa A, Ferracini R. “Bone invading NSCLC cells produce IL-7: mice model and human histologic data.” BMC Cancer. 2010 Jan 12;10(1):12.

7. Boccalatte FE, Voena C, Riganti C, Bosia A, D'Amico L, Riera L, Cheng M, Ruggeri B, Jensen ON, Goss VL, Lee K, Nardone J, Rush J, Polakiewicz RD, Comb MJ, Chiarle R, Inghirami G.  “The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALC”. Blood. 2009,Mar 19;113(12):2776-90.

CAPITOLO SU LIBRO. Lucia D’Amico, Ilaria Roato. 2012 Osteoclasts: Morphology, Functions and Clinical Implications.  Editors: Alexander J. Brown and Johanna S. Walker. Nova Science Publishers.

Proceedings:

Satolli M., Roato I., D’amico L, Mecca C., Ferracini R., Bussolati G., De Giuli M., Garetto M., Gianruggero f, Ciuffreda L., Mussa A. Mechanisms of bone metastases in gastric carcinoma (gc): preliminary results of a biological and clinical study. Annals of Oncology 2010, 21:1-132

Roato I, D’Amico L., Bertolini G., Sozzi G.,  Patanè S., Bussolati B., Cilli M., Ferracini R.
Cancer stem cells isolated from osteotropic tumors promote bone metastases. Congresso scientifico internazionale dell’ IBMS (International Bone & Mineral Society)11th International Conference on Cancer- Induced Bone Disease. Dal  30/11/2011 al 03/12/2011, Chicago, USA.

L. D’Amico,  Patanè S. , Grange C. ,Bussolati B. , Cilli M., D’Amelio P., Isaia GC., Ferracini R. , Roato I . Breast cancer stem cells  metastatize to bone in a human in mice model. American Society of Bone and Mineral Research, Annual Meeting, 16-20 Settembre 2011, San Diego, California, USA.

10 riunione Nazionale Forum in Bone and Mineral Research Torino, 18-19 Febbraio 2011. Partecipazione come Relatore.

L. D’Amico, I. Roato, S. Patanè, G. Bertolini, B. Bussolati, R. Ferracini.
Cancer stem cancer stem cells promote bone metastasis in osteotropic tumors.
3rd Joint meeting of ECTS and IBMS, 07-11 Maggio 2011, Atene, Grecia

I. Roato, L. D'Amico, F. Porta, A. Mussa,.R. Ferracini.
Role of T cells in the activation of osteoclastogenesis in phenylketonuria patients. American Society of Bone and Mineral Research, Annual Meeting, 15-19 Ottobre 2010, Toronto, Canada.

Claudia Voena, Elena Panizza, Lucia D'Amico, Chiara Ambrogio, Martinengo Cinzia, Francesco Boccalatte, Ludovica Riera, Lisa Bonello, Roberta Pulito, Jorg Hamm, Mangeng Cheng, Bruce Ruggeri, Ting-Lei Gu, Roberto D. Polakiewicz, Enzo Medico, Roberto Chiarle, Giorgio Inghirami.
EML4-ALK signaling is required for the maintenance of neoplastic phenotype of non-small cell lung cancer cells: Novel strategy for lung cancer-tailored therapies. AACR 101st Annual Meeting 2010, Apr 20, 2010,Washington, DC.

Voena C,  Panizza E, Pellegrino E, D’Amico L,  Boccalatte F E,  RuggeriB.,Polakiewicz R D, Medico E, Chiarle R, Inghirami G.
EML4-ALK signaling is required for the maintenance of neoplastic phenotype of non-small cell lung cancer cells: novel strategy for lung cancer tailored therapies. 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics – Berlino, 16-20 Novembre 2010

Davide Caldo, Ilaria Roato, Lucia D’Amico, Riccardo Ferracini.
“Rethinking Periprosthetic Osteolisys through Osteoimmunology: Peripheral Blood Spontaneous Osteoclastogenesis and Effector T-Cells.”. Annual Meeting of the Orthopaedic Research Society, 6-9 Marzo 2010 New Orleans, LA.

F.Boccalatte, C.Voena, C.Riganti, L. D’Amico, R. Chiarle, and G. Inghirami.
Phosphoproteomic profiling of Anaplastic Large Cell Lymphoma identifies ATIC as a new regulated target of the oncogenic kinase NPM_ALK”- “Cnio Center, Marzo 2008 Madrid.

26-27 giugno 2009. Partecipazione al “Forum in Bone and Mineral Research” ad Abano Terme, Padova di cui sono membro del Forum dal 2009.

Congresso scientifico internazionale dell’ IBMS (International Bone & Mineral Society) 11th International Conference on Cancer- Induced Bone Disease. Dal  30/11/2011 al 03/12/2011, Chicago,  USA.

American Society of Bone and Mineral Research, Annual Meeting, 16-20 Settembre 2011, San Diego, California, USA.

10 riunione Nazionale Forum in Bone and Mineral Research Torino, 18-19 Febbraio 2011. Partecipazione come Relatore.

3rd Joint meeting of ECTS and IBMS, 07-11 Maggio 2011, Atene, Grecia.

Ultimo aggiornamento: 05/02/2013 09:52
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