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Laura Sponton

  • Dottorato: 26° ciclo
  • Matricola: 335220

Attività di ricerca

Identification of tumor specific antigens associated with RET/PTC3 expression

Occhipinti S, Sponton L, Rolla S, Caorsi C, Novarino A, Donadio M, Bustreo S, Satolli MA, Pecchioni C, Marchini C, Amici A, Cavallo F, Cappello P, Pierobon D, Novelli F, Giovarelli M. Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patientsClin Cancer Res, 2014

- Sergio Occhipinti, Laura Sponton, Cristiana Caorsi, Augusto Amici, Cristina Marchini, Elena Quaglino, Anna Novarino, Michela Donadio, Libero Ciuffreda, Anna Sapino, Francesco Novelli, Mirella Giovarelli (2011). DNA vaccines coding for chimeric human/rat HER2 as innovative immunotherapeutic tools for the treatment of HER2+ cancer patients. In: Nuovi orientamenti della patologia molecolare. Sassari, 18 - 19 novembre, Sassari: Scuola Dianzani, p. 6-6

- Sergio Occhipinti, Laura Sponton, Cristiana Caorsi, Augusto Amici, Cristina Marchini, Elena Quaglino, Anna Novarino, Michela Donadio, Francesco Novelli, Mirella Giovarelli (2011). Dendritic cells transfected with ErbB-2 rat/human hybrid plasmid elicit an effective T cells response in ErbB-2+ cancer patients. In: Abstract book. Ascoli Piceno, 15-17 settembre, Ascoli Piceno: GVC Ascoli Piceno, p. 36-36

- Laura Sponton, Sergio Occhipinti, Francesco Novelli, Mirella Giovarelli (2011). High Mobility Group Box 1 (HMGB1) Expands CD4+CD25+Foxp3+ T Cells and Increases the Expression of CD39. In: Cytokine +. Firenze, 9 - 12 ottobre, Firenze: International Cytokine Society, p. 19-19

- Sergio Occhipinti, Laura Sponton, Cristiana Caorsi, Augusto Amici, Cristina Marchini, Guido Forni, Anna Novarino, Michela Donadio, Libero Ciuffreda, Anna Sapino, Giorgio Inghirami, Francesco Novelli, Mirella Giovarelli (2011). Dendritic cells transfected with DNA encoding ErbB2 rat/human chimeric plasmids are able to activate in vitro a specific T cell response in ErbB2+ cancer patients. In: Abstract book 2011. Mainz, Germania, 25-27 maggio, Mainz: CIMT, p. 62-62

- Sergio Occhipinti, Laura Sponton, Cristiana Caorsi, Augusto Amici, Cristina Marchini, Elena Quaglino, Anna Novarino, Michela Donadio, Francesco Novelli, Mirella Giovarelli (2011). Effective T cells response can be elicited in ErbB-2+ cancer patients by ErbB-2 rat/human hybrid plasmid transfection of dendritic cells. In: Minerva Medica. Riccione, 28 settembre - 1 ottobre, TORINO: Edizioni Minerva Medica, vol. 102, p. 180-180

- Sergio Occhipinti, Laura Sponton, Cristiana Caorsi, Augusto Amici, Cristina Marchini, Elena Quaglino, Anna Novarino, Michela Donadio, Libero Ciuffreda, Francesco Novelli, Mirella Giovarelli (2011). Dendritic cells transfected with ErbB2 rat/human hybrid plasmid elicit an effective T cells response in ErbB2+ cancer patients. In: Poster abstract book. North Bethesda, USA, 4 - 6 novembre, North Bethesda: SITC, p. 135-135

- Minero V.G., De Stefanis D., Sponton L., Costelli P., Bonelli G., Baccino F.M. (2009). Il blocco in G2/M indotto dal tassolo sensibilizza le cellule di epatocarcinoma umano Huh7 all'apoptosi da TNFa. In: Firenze, 02/12/2009-04/12/2009, vol. poster n. P11

- V.G. Minero, D. De Stefanis, L. Sponton, P. Costelli, F.M. Baccino, G. Bonelli (2009). G2/M arrest induced by paclitaxel sensitizes Huh7 hepatoma cells to TNFa-dependent apoptosis. In: Novara, 11/12/2009-12/12/2009, p. 22-22

- 9th Joint Meeting of ICS-ISICR cytokines and interferons: from the bench to the bedside, Firenze - Italy, 9-12 ottobre 2011. (Poster)

2011

- 16 marzo 2011 Seminario Roberto S. Accolla, Giovanna Tosi “Intrinsic and adaptive immunity: the dual function CIITA as viral restriction factor and as inducer of specific immunity against tumors”.

- 21 marzo 2011 Seminario Federico Garrido “The escape of cancer from immune surveillance: MHC expression and tumor rejection”.

- 10-17-24-31 maggio 2011, 7-14 giugno 2011 Corso Prof. Guido Forni “Corso Monografico sull'Immunologia dei Tumori”.

- 29 maggio 2011 “The Biology of Cancer Oncogene and Microenviroment” Fondazione Piemontese per la Ricerca sul Cancro –ONLUS.

- 21 giugno 2011 Workshop “Learn more about primary cells, cell culture reagents and mycoplasma prevention” organizzato da PB Internetional.

- 12-13 settembre 2011 Corso Prof. Caselle “Ricerca Bibliografica e Database” 

- 19 settembre 2011 D-Day, Scuola di Dottorato in Scienze della Vita e della Salute

- 19 ottobre 2011 Seminario  Mariano Barbacid “Mouse Models of Cancer: A Genetic Tool to Validate Therapeutic Targets”.

- 30 novembre 2011 Seminario Elena Giglia “Open Access, i vantaggi per chi fa ricerca”.

- 5 dicembre 2011 Seminario Julie Gehl “Optimising gene electrotransfer to skin and muscle clinical exprerience with electroporation based drug and gene delivery”.

- 14 dicembre 2011 VI Giornata del Dottorato di Immunologia e Biologia Cellulare.

 

2012

- 11 gennaio 2012 Seminario Pier Paolo Di Fiore "Endocytosis, Stem cells and Cancer".

- 19 gennaio 2012 Seminario Ario De Marco "Biomedical application of the recombinant antibodies technology".

- 25 gennaio 2012 Seminario Pier Giuseppe Pelicci "Regulation of Self-renewal in Cancer stem cells".

- 31 gennaio 2012 Seminario Giuseppe Maruccio "Multipurpose biochips toward on-chip medicine".

- 27-28 febbraio 2012 Corso Prof. Paolo Provero "Corso di biostatistica".

- 27 marzo 2012 Seminario Ethan M Shevach "Foxp3+ T Regulatory Cells: What do they really do?".

- 29 April - 04 May 2012 “Workshop on Surgical Techniques in the Laboratory Mouse” The Jackson Laboratory, Bar Harbor, Maine, USA.

- 7 giugno 2012 Workshop "Cancer Day: from metabolism to immunotheraphy" organizzato da Paola Cappello e Franco Novelli

- 14 settembre 2012 D-Day, Scuola di Dottorato in Scienze della Vita e della Salute

- 11 ottobre 2012 - Ganes C. Sen, PhD “Innate Immune Response to Virus Infection” - Solis Cohen Auditorium, Jefferson Alumni Hall, Jefferson University, Philadelphia, USA

- 5 dicembre 2012 – Adam P. Dicker, MD, PhD and Ulrich Rodeck, MD, PhD “Translational Opportunities in Oncology: from Zebrafish to Mice to Patients – Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

 

2013

- 30 gennaio 2013 - Steven A. Rosenberg, MD, PhD “Autologous T Cells as a Personalized Treatment for Patients with Cancer” – The Wistar Institute, U Penn, Philadelphia, USA

- 6 febbraio 2013 – Brian Kolbilka, MD, NOBEL PRIZE in Chemistry 2012 “Structural Insights into G Protein Coupled Receptor Activation” – Hamilton Building, Connelly Conference Hall, Jefferson University, USA

- 21 febbraio 2013 – Allen Buskirk, PhD “Nascent peptides that stall ribosomes during protein synthesis” - Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

- 10 aprile 2013 – Michael R. Betts, PhD “Function and dysfucnton of CD8+ T cells in acute HIV infection” – Jefferson Alumni Hall, Jefferson University, Philadelphia, USA

- 6 maggio 2013 – Laurence C. Eisenlohr, VMD, PhD “Where Do MHC Class II-bound Peptides Come From? Implications for Immunity to Viruses, Self and Cancer” - MBC Via Nizza 52, Aula Aristotele, University of Turin, Torino, Italy

- 16 maggio 2013 – John C. Williams, PhD “Meditopes – Non-covalent functionalization of therapeutic monoclonal anribodies”- Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

- 7 giugno 2013 – Richard C. Wender, MD “From Prevention to End of Life – Primary Care Research and Cancer” - Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

- 11 settembre 2013 – Richard G. Pestell, MD, PhD “Cell cycle control of Genomic Signaling” - Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

- 9 ottobre 2013 - Massimo Cristofanili, MD, FACP “Inflammatory Breast Cancer (IBC): A unique disease model for epidemiology, biology and clinical research” – Jefferson Medical College, Jefferson University, Philadelphia, USA

- 16 ottobre 2013 – Saraswati Sukumar, PhD “A Circulating free DNA assay, cMethDNA, that Detects and Predicts Response to Metastatic Breast Cancer” - Bluemle Life Sciences Building, Jefferson University, Philadelphia, USA

 

2014

 - 27 maggio 2014 Seminario Dr Marcus Sperandio “Immune responses and primary hemostasis in the developing mouse fetus in vivo”

 - 12 giugno 2014 Seminario Dr. Antoine E. Karboub "Microenvironmental regulation of breast cancer metastasis"

 - 16 luglio 2014 Prof. Ingrid Winship "Translating research into clinical genetic practice"

- 29 ottobre 2014 Seminario di Dipartimento "Basic Scientists meet Clinicians to fill the gap"

 

Sep 2012 –  Nov 2013

Kimmel Cancer Center - Thomas Jefferson University

Department of Microbiology and Immunology, Philadelphia, USA

Prof. Laurence C. Eisenlohr’s laboratory.

Ultimo aggiornamento: 18/11/2014 10:46
Location: https://dott-mm.campusnet.unito.it/robots.html
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