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Dott.ssa Nicole Finesso

  • Dottorato: 29° ciclo
  • Matricola: 791263

Tesi di dottorato

Development of nanotherapeutics systems for infected chronic wound management.

Attività di ricerca

Development of  chitosan-shelled oxygen-loaded nanocarriers conjugated with drugs to counteract microbial infections.

Development of oxygen nanocarriers targeting hypoxia-associated diseases.

Effects of antimicrobial-coupled nanocarriers and nanocarriers alone on MRSA, S. pyogenes,  C. albicans and C. glabrata growth.

Oxygen nanocarrier effects on wound healing abilities of human cells.

Nanocarrier biocompatibility studies on human cells. 

Functional roles of matrix-extracellular molecules during remodeling of chronic wound healing. 

2017

ARGENZIANO M., BANCHE G., LUGANINI A., FINESSO N., ALLIZOND V., GULINO G.R., KHADJAVI A., SPAGNOLO R., TULLIO V., GIRIBALDI G., GUIOT C., CUFFINI A.M., PRATO M., CAVALLI R. (2017).  Vancomycin-loaded nanobubbles: A new platform for controlled antibiotic delivery against methicillin-resistant Staphylococcus aureus infections. International Journal of Pharmacology 523(1):176-188.

 

2015

BANCHE G., PRATO M., MAGNETTO C., ALLIZOND V., GIRIBALDI G., ARGENZIANO M., KHADJAVI A., GULINO G. R., FINESSO N., MANDRAS N., TULLIO V., CAVALLI R., GUIOT C., CUFFINI A. M. (2015). Antimicrobial chitosan nanodroplets: new insights for ultrasound-mediated adjuvant treatment of skin infection. Future Microbiology 10: 929-939.

2017

BANCHE G., FINESSO N., ALLIZOND V., PRATO M., LUGANINI A., TROIA A., GIRIBALDI G., KHADJAVI A., TULLIO V., MANDRAS N., ARGENZIANO M., CAVALLI R., GUIOT C., CUFFINI A.M. (2017). Antibacterial activity of chitosan-shelled oxygen-loaded nanobubbles and nanodroplets against MRSA in chronic wounds. 45th National Congress of the Italian Society of Microbiology in Genova, 27-30/9/2017. Poster presentation.

ARGENZIANO M., BANCHE G., LUGANINI A., FINESSO N., ALLIZOND V., GULINO GR., KHADJAVI A., SAPGNOLO R., TULLIO V., GIRIBALDI G., GUIOT C., CUFFINI A.M., PRATO M., CAVALLI R. (2017). Vancomycin-loaded nanobubbles as innovative and effective nanocarriers for controlled topical antibiotic delivery against methicillin-resistant Staphylococcus aureus infections. 21th International Symposium on Microencapsulation in Faro, Portugal, 27-29/9/2017. Poster presentation.

ARGENZIANO M., FINESSO N., D'ALESSANDRO S., FUMAGALLI M., GENOVA T., TROIA A., GIRIBALDI G., GUIOT C., CUFFINI A.M., DELL'AGLI M., BASILICO N., CAVALLI R., PRATO M. (2017).  Comparative evaluation of different chitosan species and derivatives as candidate biomaterials for oxygen-loaded nanodroplet formulations to treat chronic wounds. 10th International Conference of Advanced Nano Materials (ANM2017) (Nanomedicine session) in Guildford (University of Surrey), UK, 11-13/09/2017. Abstract book, page 376. 

FINESSO N., G. BANCHE, V. ALLIZOND, M. PRATO, A. LUGANINI, A. TROIA, G. GIRIBALDI, A. KHADJAVI, V. TULLIO, N. MANDRAS, R. CAVALLI, C. GUIOT, A.M. CUFFINI. (2017). Chitosan-shelled oxygen-loaded nanobubble and nanodroplet comparison: new insights into infected chronic wounds caused by MRSA. 27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID2017) in Vienna, Austria, 22-25/04/2017. Poster presentation. 

 

2016

FINESSO N., LUGANINI A., BANCHE G., MANDRAS N., ALLIZOND V., ARGENZIANO M., MAGNETTO C., SCALAS D., ROANA J., GIRIBALDI G., GUIOT C., CAVALLI R., TROIA A., TULLIO V., CUFFINI A.M., PRATO M. (2016). Confocal microscopy as a promising tool to predict the antimicrobial efficacy of chitosan nanodroplets. 2nd Microscopy Congress" in London, UK, 14-15/11/2016. Abstract book, P6, page no.9. Poster presentation.

FINESSO N., LUGANINI A., BANCHE G., ALLIZOND V., GULINO G.R., GENOVA T., MAGNETTO C., TULLIO V., GIRIBALDI G., CUFFINI A.M., PRATO M. (2016). Antimicrobial oxygen-loaded nanobubbles as promising tools to promote wound healing in hypoxic human keratinocytes."Hypoxia 2016" in Nantes, France, 06-07/10/2016. Abstract book, pages 56-57. Oral presentation. 

FINESSO N., LUGANINI A., BANCHE G., ALLIZOND V., GULINO G.R., GENOVA T., MAGNETTO C., TULLIO V., GIRIBALDI G., CUFFINI A.M., PRATO M.  (2016). Oxygen-loaded chitosan/perfluoropentane nanobubbles as promising antimicrobial devices to promote wound healing. 4th International Conference on Antimicrobial Research (ICAR2016) in Torremolinos-Malaga, Spain, 30/06-01/07/2016. Abstract book, page 129. Oral presentation. 

FINESSO N., PRATO M., BANCHE G., ALLIZOND V., MAGNETTO C., ARGENZIANO M., LUGANINI A., KHADJAVI A., TROIA A., GIRIBALDI G., CAVALLI R., GUIOT C., CUFFINI A.M. (2016) . Chitosan/2H,3H-decafluoropentane nanodroplets as anti-bacterial and skin-friendly devices for ultrasound-triggered transdermal delivery.  4th International Conference on Antimicrobial Research (ICAR2016) in Torremolinos-Malaga, Spain, 30/06-01/07/2016. Abstract book, page 187. Poster presentation. 

PRATO M., ARGENZIANO M., BANCHE G., FINESSO N., LUGANINI A., ALLIZOND V., GULINO G.R., KHADJAVI A., SOSTER M., GIRIBALDI G., GUIOT C., CUFFINI A.M., CAVALLI R. (2016). Vancomycin-loaded dextran sulfate/perfluoropentane nanobubbles for controlled drug release against methicillin-resistant Staphylococcus aureus infections. 4th International Conference on Antimicrobial Research (ICAR2016) in Torremolinos-Malaga, Spain, 30/06-01/07/2016. Abstract book, page 246. Oral presentation.

PRATO M., FINESSO N., MANDRAS N., SCALAS D., ROANA J., MAGNETTO C., LUGANINI A., GULINO G.R., GENOVA T., TROIA A., GIRIBALDI G., CUFFINI A.M., TULLIO V. (2016). Oxygen-loaded chitosan/2H,3H-decafluoropentane nanodroplets as anti-fungal devices to promote wound healing. 4th International Conference on Antimicrobial Research (ICAR2016) in Torremolinos-Malaga, Spain, 30/06-01/07/2016. Abstract book, page 204. Poster presentation. 

 

2015

ARGENZIANO M., SOSTER M., PRATO M., BANCHE G., FINESSO N., ALLIZOND V., LUGANINI A., KHADJAVI A., GIRIBALDI G., CUFFINI A. M., GUIOT C., CAVALLI R. (2015). Vancomycin-loaded dextran sulfate-shelled/perfluoropentane-cored nanobubbles for antibiotic transdermal delivery. Crossing Biological Barriers - Advances in Nanocarrier Design for Targeted Drug Delivery in Dresden, Germany, 9-11/11/2015. Abstract book page 55. Oral presentation. 

FINESSO N., BANCHE G., LUGANINI A., MAGNETTO C., ARGENZIANO M., SOSTER M., ALLIZOND V., GRIBAUDO G., TULLIO V., GUIOT C., CAVALLI R., CUFFINI A. M., PRATO M., GIRIBALDI G. (2015). Antimicrobial effects against MRSA and C. albicans of chitosan-shelled oxygenloaded nanobubbles and nanodroplets. 27th National Meeting "A. Castellani" of Biochemistry PhD Students in Brallo di Pregola (PV), 8-12/6/2015. Poster presentation. 

PRATO M., BANCHE G., MAGNETTO C., ALLIZOND V., GIRIBALDI G., ARGENZIANO M.,  KHADJAVI A., GULINO G.R., FINESSO N., MANDRAS N., TULLIO V., CAVALLI R., GUIOTC., CUFFINI A.M. (2015). Chitosan-shelled oxygen-loaded  nanodroplets as innovative and nonconventional antimicrobial tools against methicillin-resistant Staphylococcus aureus and Candida albicans: new perspectives for an ultrasound-mediated adjuvant treatment of infected chronic wounds. 25th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID2015) in Copenhagen, Denmark, 25-28/04/2015 (P1373). Poster presentation. 

 

 

Oral presentations

2016

 IV International Conference on Antimicrobial Research (ICAR2016)

 

Poster presentations

2017

27th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID2017), Vienna (Austria). 

2016

4th International Conference on Antimicrobial Research (ICAR2016), Torremolinos-Malaga (Spain). 

2015

27th National Meeting "A. Castellani" of Biochemistry PhD Students,  Brallo di Pregola (Pv).

 

Partecipations

2015

28th Annual Conference of Italian Association of Cell Cultures, Naples, November 16-18, 2015.

International conference "From Signal Transduction to Cancer Precision Medicine", Candiolo, June 6-7, 2015.

Meeting "Frontiers in Regenerative Medicine", Turin, February 19-20, 2015.

2014

42th Congress of Italian Society of Microbiology, Turin, 28 September- 1 October 2014.

Workshop of Italian Society of Cancerology "Targeted Therapy of Cancer: where we are heading", Turin, June 27, 2014.

 2015

"Circular and linear Non-Coding RNAs in tumorigenesis", Dr. Pandolfi, Turin, May 6, 2015.

 

2014

"Epigenetic control of chromatin-dependent transcription",  Prof. Cheng-Ming Chiang, Turin, October 17, 2014.

"Antiviral resistance and cross resistance in HCMV infected stem cell transplant patients and in newborns", Prof. Jahn, Turin, June 11, 2014.

"Epigentic mechanisms: biology and bioinformatics", Prof. Oliviero, Prof. Policriti, Prof. Mraz, Turin, May 23, 2014.

"Fast-Tracking Molecular Diagnostics in Oncology", Prof. Gallagher, Turin, February 3, 2014.

"The role of the transcription factor Otx2 in embryonic pluripotent stem cells (ESCs and EpisCs), Prof. Simeone, Turin, Jenuary 23, 2014.

"Genetica della Corea di Huntington", Prof. Cattaneo, Turin, February 11, 2014.

 

2016

"Giornata dedicata alla valorizzazione delle competenze dei Dottori di ricerca e al postdoc", Turin, October 4 , 2016.

D-day, Turin, September 15 , 2016.

"Enabling technologies in 3D cancer organoids", Turin, March 8/9, 2016. 

 

 2015

D-day, Turin, September 16, 2015.

Joined Inauguration of UNITO Doctoral School activities, Turin, February 3 , 2015.

"Il trasferimento di conoscenze in Ateneo: dalla ricerca alla valorizzazione dell'innovazione", Turin, February 3, 2015.

2015

 Scientific English, Prof. , Turin, November 2015 - March 2016 (in progress). (organized by Doctoral School in Life and Health Sciences)

Statistical method for biological data, Prof. Provero, Turin, June - July 2015. (organized by Doctoral School in Life and Health Sciences)

 

2014

Introduction to Bibliographic Research, Turin , September 16 - 23, 2014. (organized by Doctoral School in Life and Health Sciences)

 

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