Dottorato in Medicina Molecolare

- Whole genome sequencing reveals genetic heterogeneity of G3P[8] rotaviruses circulating in Italy.

Medici MC, Tummolo F, Martella V, Arcangeletti MC, De Conto F, Chezzi C, Magri' A, Fehèr E, Marton S, Calderaro A, Bànyai K.

Infect Genet Evol. 2016 Jun;40:253-61. doi: 10.1016/j.meegid.2016.03.013. Epub 2016 Mar 12.

 

1st year PhD 2015-2016

- HER2 amplification as a “molecular bait” for trastuzumab-emtansine (T-DM1) precision chemotherapy to overcome anti-HER2 resistance in HER2 positive metastatic colorectal cancer: the Heracles-Rescue trial.

S. Siena, A. Bardelli, A. Sartore-Bianchi, C. Martino, G. Siravegna, A. Magrì, F. Leone, V. Zagonel, S. Lonardi, A. Amatu, F. Tosi, P. Racca, A. Ponzetti, F. Ciardiello, S. Marsoni.

Abstract at GI ASCO Cancer Symposium, January 21-23, 2016.

 

1st year PhD 2015-2016

- AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

5-9 November 2015, Hynes Convention Center, Boston, MA, USA

 

1st year PhD 2015-2016

- VEGF removal enhances the antitumor effect of BRAF inhibition by reprogramming the circuits between cancer and stroma. 17 November 2015, IRCCS Candiolo, Valentina Comunanza

- Regulation of Colorectal Cancer Stem Cells by Cytokine Networks: implications in self-renewal and resistance to therapies. 24 November 2015, IRCCS Candiolo, Viola Bigatto

- Role of alpha6 integrin in pericytes dynamics and tumor vessels normalization. 1 December 2015, IRCCS Candiolo, Giulia Chiaverina

- "Regulation of self renewal in Cancer Stem Cells"  Friday 11 December 2015, IRCCS Candiolo, Prof. Pier Giuseppe Pelicci 

- Semaphorin 6A and responsiveness to anti-EGFR targeted therapies in colorectal cancer. 15 December 2015, IRCCS Candiolo, Chiara Battistini

- Strategies to improve half-life and potency of a Met therapeutic antibody. 22 December 2015, IRCCS Candiolo, Simona Cignetto

- Collective directional migration in epithelial 3d models. 12 January 2016, IRCCS Candiolo Alberto Puliafito 

- High-throughput screening to unravel the influence of protein phosphatases on VEGF-A signaling. 19 January 2016, IRCCS Candiolo Maria Alvaro

- "The impact of human retrotransposons on cancer" by Dr. Szilvia Solyom  January 2016, 26th - at IRCC

- Role of the endoplasmic reticulum in the control of neuropilin 1 traffic and endothelial cell adhesion. 2 February 2016, IRCCS Candiolo, Giulia Villari 

- Intercepting acquired resistance to targeted therapies: how and when?. 9 February 2016, IRCCS Candiolo Mariangela Russo

- Immunotherapy, microbiota and cancer, February 12, 2016 IRCCS Candiolo Maria Rescigno

- Caspase-mediated cleavage of MRCKα determines actin-myosin contraction and epithelial cell extrusion. 1 March 2016, IRCCS Candiolo Paolo Gagliardi

- Preclinical activity of Cytokine Induced Killer Cells (CIK) against sarcomas. 8 March 2016, IRCCS Candiolo Giulia Mesiano

- RNA-based identification of actionable oncogenic drivers in colorectal cancer. 15 March 2016, IRCCS Candiolo Sara Bellomo

- "The transparent editorial process, data reproducibility and research integrity at EMBO" Prof. Roberto Buccione held in the IRCC, Tuesday 22 March 2016

- "Breast Cancer stem Cells targeting: a new step for intratumoral heterogeneity in the light of personalized medicine" by Prof. Emmanuelle Charafe Jauffret, Aix-Marseille Université, CRCM, Institut Paoli-Calmettes, CNRS, Marseille - Friday 25 March 2016 IRCCS Candiolo

- Tfeb inhibits differentiation of coronary smooth muscle cells and fibroblasts by upregulation of TGF-β and Notch pathways repressors. 29 March 2016, IRCCS Candiolo Elena Astanina

- TFEB governs a transcriptional program essential for angiogenic activities of VEGFR2. 5 April 2016, IRCCS Candiolo Gabriella Doronzo

- Xenospheres: a comprehensive patient-derived in vitro model to study response and resistance to targeted therapies in mCRC. 26 April 2016, Paolo Luraghi

- "AIRC Support to Cancer Research: Strategies and Perspectives" by Prof. Federico Caligaris-Cappio, Scientific Director, Italian Association for Cancer Research - Milano. Friday 29 April 2016

- PPFIA1 drives active α5β1 integrin recycling from the TGN to control fibronectin fibrillogenesis and vascular morphogenesis. 3 May 2016, IRCCS Candiolo Donatella Valdembri

- Ras and Rab interacting protein 2 (RIN2) controls cell adhesion dynamics and signaling: implications for cancer angiogenesis and invasion. 10 May 2016, IRCCS Candiolo Chiara Sandri

- Generation of  a platform of gastro-esophageal PDXs to identify and validate molecular targets. 17 May 2016, IRCCS Candiolo Prof. Silvia Giordano

- AGNOSTOS Project: a platform to unveil the mysteries of cancer of unknown primary (CUPS). 24 May 2016, Silvia Benvenuti 

- "Control of cell identity by polycomb group proteins " by Prof. Davide Pasini, Director of the Epigenetic mechanisms in stem cell differentiation and oncogenesis Unit - IEO Milano. IRCCS Candiolo, Friday 27 May 2016

- A potential strategy to counteract minimal residual disease in colorectal cancer after EGFR blockade.. 31 May 2016, IRCCS Candiolo Barbara Lupo

- Exploring glioblastoma heterogeneity at cancer stem cell level. 7 June 2016, Francesca De Bacco

- Precision oncology between challenges and opportunities: The example of colorectal cancer. 10 June 2016, IRCCS Candiolo Prof. Livio Trusolino

- "Visualizing spatio-temporal signaling networks regulating cell fate and morphogenesis" by Prof. Olivier Pertz, Cellular Dynamics Lab - Institute of Cell Biology - University of Bern (Switzerland). Friday 17 June 2016 IRCCS Candiolo

- The GEA platform as a tool to model gastric cancer therapy: focus on HER2. 21 June 2016, IRCCS Candiolo Cristina Migliore

- Cancer evolution as a therapeutic opportunity. 28 June 2016, IRCCS Candiolo Prof. Alberto Bardelli 

- Integrated transcriptomic analysis of coding and non-coding RNAs involved in gene regulatory networks sustaining Sprouting Angiogenesis. 5 July 2016, Stefania Rosano

- Patient-derived tumor xenograft model to study intratumour heterogeneity of epithelial ovarian carcinomas. 15 July 2016, Prof. Maria Flavia Di Renzo

- Transcriptomic and mutational analyses of paired primary/recurrent intrahepatic cholangiocarcinoma. 19 July 2016, Caterina Peraldo Neia